Researchers at the University of Rochester Medical Center have discovered that a certain type of human cell which was transplanted into rats with spinal cord injuries was able to repair the damage to the spine but also helped the rats recover function.
The study was published in early March in the journal PLoS ONE, and describes how human astrocytes, the main supporting cells of the central nervous system, derived from human stem cells, may be a crucial component in the treatment of spinal cord injuries and other CNS illnesses and disorders.
The lead researcher and study author, Chris Proschel, PhD, and professor of Genetics at the University of Rochester Medical Center commented on the study:
“We’ve shown in previous research that the right types of rat astrocytes are beneficial, but this study brings it up to the human level, which is a huge step. What’s really striking is the robustness of the effect. Scientists have claimed repair of spinal cord injuries in rats before, but the benefits have been variable and rarely as strong as what we’ve seen with our transplants.”
Josyann Abisaab is a graduate of the University of Rochester School of Medicine, where ongoing research is leading the way in many a crucial aspects of human biology, physiology and their clinical implications.